Thrombocythaemia Myelofibrosis - Pipeline Review, H1 2013

Thrombocythaemia Myelofibrosis - Pipeline Review, H1 2013

$2,000.00

Publication ID
GMD0513158
Publication Date
May 27, 2013
Pages
54
Regions Covered
Publisher
Global Markets Direct's, 'Thrombocythaemia Myelofibrosis Pipeline Review, H1 2013', provides an overview of the indication's therapeutic pipeline. This report provides information on the therapeutic development for Thrombocythaemia Myelofibrosis, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Thrombocythaemia Myelofibrosis. Thrombocythaemia Myelofibrosis Pipeline Review, Half Year is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team.
 
Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.
 

Scope

  • A snapshot of the global therapeutic scenario for Thrombocythaemia Myelofibrosis.
  • A review of the Thrombocythaemia Myelofibrosis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • Coverage of products based on various stages of development ranging from discovery till registration stages.
  • A feature on pipeline projects on the basis of monotherapy and combined therapeutics.
  • Coverage of the Thrombocythaemia Myelofibrosis pipeline on the basis of route of administration and molecule type.
  • Key discontinued pipeline projects.
  • Latest news and deals relating to the products.
 

Reasons to buy

  • Identify and understand important and diverse types of therapeutics under development for Thrombocythaemia Myelofibrosis.
  • Identify emerging players with potentially strong product portfolio and design effective counter-strategies to gain competitive advantage.
  • Plan mergers and acquisitions effectively by identifying players of the most promising pipeline.
  • Devise corrective measures for pipeline projects by understanding Thrombocythaemia Myelofibrosis pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline.

Table of Contents 2

List of Tables 4
List of Figures 4
Introduction 5
Global Markets Direct Report Coverage 5
Thrombocythaemia Myelofibrosis Overview 6
Therapeutics Development 7
An Overview of Pipeline Products for Thrombocythaemia Myelofibrosis 7
Thrombocythaemia Myelofibrosis Therapeutics under Development by Companies 9
Mid Clinical Stage Products 10
Comparative Analysis 10
Early Clinical Stage Products 11
Comparative Analysis 11
Thrombocythaemia Myelofibrosis Therapeutics - Products under Development by Companies 12
Companies Involved in Thrombocythaemia Myelofibrosis Therapeutics Development 13
Gilead Sciences, Inc. 13
Novartis AG 14
Incyte Corporation 15
Thrombocythaemia Myelofibrosis - Therapeutics Assessment 16
Assessment by Monotherapy Products 16
Assessment by Route of Administration 17
Assessment by Molecule Type 19
Drug Profiles 21
panobinostat - Drug Profile 21
Product Description 21
Mechanism of Action 21
R&D Progress 21
momelotinib dihydrochloride - Drug Profile 26
Product Description 26
Mechanism of Action 26
R&D Progress 26
ruxolitinib - Drug Profile 28
Product Description 28
Mechanism of Action 28
R&D Progress 28
buparlisib - Drug Profile 32
Product Description 32
Mechanism of Action 32
R&D Progress 32
AUY-922 - Drug Profile 35
Product Description 35
Mechanism of Action 35
R&D Progress 35
simtuzumab - Drug Profile 37
Product Description 37
Mechanism of Action 37
R&D Progress 37
NS-018 - Drug Profile 39
Product Description 39
Mechanism of Action 39
R&D Progress 39
Thrombocythaemia Myelofibrosis Therapeutics - Drug Profile Updates 40
Thrombocythaemia Myelofibrosis - Product Development Milestones 50
Featured News & Press Releases 50
Apr 20, 2012: Incyte Announces EU Regulatory Milestone From Novartis For Ruxolitinib 50
Dec 08, 2010: Incyte Provides Positive Phase II Trial Results Of INCB18424 In Myeloproliferative Neoplasms 50
Oct 18, 2010: S*BIO's SB1518 Receives Orphan Drug Designation From European Commission For Treatment Of Myelofibrosis 52

Appendix 53

Methodology 53

Coverage 53
Secondary Research 53
Primary Research 53
Expert Panel Validation 53
Contact Us 54
Disclaimer 54
 

List of Tables

Number of Products Under Development for Thrombocythaemia Myelofibrosis, H1 2013 7
Products under Development for Thrombocythaemia Myelofibrosis - Comparative Analysis, H1 2013 8
Number of Products under Development by Companies, H1 2013 9
Comparative Analysis by Mid Clinical Stage Development, H1 2013 10
Comparative Analysis by Early Clinical Stage Development, H1 2013 11
Products under Development by Companies, H1 2013 12
Gilead Sciences, Inc., H1 2013 13
Novartis AG, H1 2013 14
Incyte Corporation, H1 2013 15
Assessment by Monotherapy Products, H1 2013 16
Assessment by Stage and Route of Administration, H1 2013 18
Assessment by Stage and Molecule Type, H1 2013 20
Thrombocythaemia Myelofibrosis Therapeutics - Drug Profile Updates 40
 

List of Figures

Number of Products under Development for Thrombocythaemia Myelofibrosis, H1 2013 7
Products under Development for Thrombocythaemia Myelofibrosis - Comparative Analysis, H1 2013 8
Products under Development by Companies, H1 2013 9
Mid Clinical Stage Products, H1 2013 10
Early Clinical Stage Products, H1 2013 11
Assessment by Monotherapy Products, H1 2013 16
Assessment by Route of Administration, H1 2013 17
Assessment by Stage and Route of Administration, H1 2013 18
Assessment by Molecule Type, H1 2013 19
Assessment by Stage and Molecule Type, H1 2013 20
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