Hyperparathyroidism – Analysis and Market Forecasts to 2019

Hyperparathyroidism – Analysis and Market Forecasts to 2019

$5,995.00

Publication ID
GDA1012748
Publication Date
October 31, 2012
Pages
70
Regions Covered
Publisher
Hyperparathyroidism – Analysis and Market Forecasts to 2019

Summary

The global hyperparathyroidism therapeutics market is forecast to grow to reach $2.6 billion by 2019. This moderate growth is primarily attributed to the increase in the hyperparathyroidism patient population and the expected launches of two novel drugs: CTAP101 and KAI-4169 IV. The major barriers for the hyperparathyroidism therapeutics market during forecast period are the introduction of bundled dialysis payment system in the US and the expected patent expirations of all three leading branded drugs in the market: Sensipar/Mimpara, Zemplar and Hectorol. The hyperparathyroidism pipeline is weak, with only seven molecules in various stages of development, including four first-in-class molecules and three me-too products. Amgen and Abbott are the leading companies in the current competitive landscape. Amgen is likely to maintain its position during the forecast period due to its acquisition in July 2012 of KAI Pharmaceuticals and its promising pipeline molecule KAI-4169.
 

Scope

  • Overview of hyperparathyroidism, including epidemiology, etiology, symptoms, diagnosis, pathophysiology, management and treatment guidelines.
  • Annualized hyperparathyroidism therapeutics market revenue, annual cost of therapy and forecast for eight years to 2019.
  • Pipeline analysis: Comprehensive data split across different phases, emerging trends and mechanisms of action under development, including calcium sensing receptor agonist, vitamin D pro-hormone, vitamin D receptor agonist and CYP24 enzyme inhibitor.
  • Analysis of the current and future market competition in the global hyperparathyroidism therapeutics market.
  • Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.
  • Key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping and implications for the hyperparathyroidism therapeutics market.
 

Reasons to buy

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the global hyperparathyroidism therapeutics market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global hyperparathyroidism therapeutics market in future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Track drug sales in the global hyperparathyroidism therapeutics market from 2011–2019.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

1 Table of Contents 5

1.1 List of Tables 7
1.2 List of Figures 8

2 Introduction 9

2.1 Catalyst 9
2.2 Related Reports 9
2.3 Upcoming Related Reports 9

3 Disease Overview 10

3.1 Etiology and Pathophysiology 11
3.1.1 Etiology 11
3.1.2 Pathophysiology 12
3.1.3 Risk Factors 13
3.1.4 Prognosis 14
3.2 Epidemiology 14
3.2.1 Prevalence 14
3.2.2 Diagnosed Prevalence 15
3.3 Symptoms 16
3.4 Diagnosis and Referral 16
3.4.1 Diagnosis 16
3.4.2 Referral 17
3.5 Treatment Guidelines 18
3.6 Disease Management 19
3.6.1 Primary Hyperparathyroidism 19
3.6.2 Secondary Hyperparathyroidism 20
3.6.3 Tertiary Hyperparathyroidism 21

4 Competitive Assessment 22

4.1 Overview 22
4.2 Strategic Competitor Assessment 22
4.3 Product Profile - Major Brands 24
4.3.1 Sensipar (cinacalcet) 24
4.3.2 Zemplar (paricalcitol) 26
4.3.3 Hectorol (doxercalciferol) 28
4.3.4 Oxarol (maxacalcitol) 29

5 Opportunity and Unmet Need 31

5.1 Overview 31
5.2 Lower Adverse Effect on Serum Calcium and Phosphorus Level 32
5.3 New Treatment Options for Primary Hyperparathyroidism 32
5.4 Disease Awareness and Screening Programs in Primary Hyperparathyroidism 32
5.5 Convenient Dosing Regimen 32
5.6 Guidelines for Tertiary Hyperparathyroidism Management 32
5.7 Pricing 33

6 Pipeline Assessment 34

6.1 Overview 34
6.2 Strategic Pipeline Assessment 34
6.3 Pipeline by Phases of Development 34
6.3.1 Phase III Pipeline 34
6.3.2 Phase II Pipeline 35
6.3.3 Phase I Pipeline 35
6.3.4 Preclinical Pipeline 35
6.3.5 Discovery Pipeline 35
6.4 Pipeline by Mechanism of Action 36
6.5 Technology Trends Analytic Framework 37
6.6 Hyperparathyroidism - Promising Drugs in Clinical Development 38
6.6.1 CTAP101 39
6.6.2 KAI-4169 IV 41

7 Clinical Trials Mapping 43

7.1 Clinical Trials by Country 43
7.2 Clinical Trials by Phase 43
7.3 Clinical Trials by Trial Status 44
7.4 Prominent Sponsors 44

8 Current and Future Players 46

8.1 Overview 46
8.2 Trends in Corporate Strategy 46
8.3 Company Profiles 47
8.3.1 Amgen Inc. 47
8.3.2 Abbott Laboratories 48
8.3.3 Cytochroma Inc. 49
8.3.4 KAI Pharmaceuticals Inc. 50
8.3.5 Other Companies in the Hyperparathyroidism Therapeutics Market 51

9 Licensing and Partnership Deals 52

9.1 Overview 52
9.2 Key Deals and Alliances in the Past 12 Months 52

10 Market Outlook 53

10.1 Seven Major Markets Overview 53
10.2 Regional Analysis 55
10.2.1 US 55
10.2.2 France 56
10.2.3 Germany 57
10.2.4 Italy 57
10.2.5 Spain 58
10.2.6 UK 58
10.2.7 Japan 59
10.3 Key Events 59
10.4 Drivers and Barriers 60
10.4.1 Drivers for the Hyperparathyroidism Market 60
10.4.2 Barriers for the Hyperparathyroidism Market 61

11 Appendix 62

11.1 Abbreviations 62
11.2 Bibliography 63
11.3 Methodology 65
11.3.1 Coverage 65
11.3.2 Secondary Research 65
11.3.3 Forecasting Methodology 66
11.3.4 Primary Research 68
11.3.5 Expert Panel Validation 69
11.4 Physicians and Specialists Included in this Study 69
11.5 About the Authors 69
11.5.1 Analysts 69
11.5.2 Global Head of Healthcare Research and Consulting 70
11.6 About GlobalData 70
11.7 Contact Us 70
11.8 Disclaimer 70
  1. Amgen Inc.
  2. Abbott Laboratories
  3. Cytochroma Inc.
  4. KAI Pharmaceuticals Inc.
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