Based on the antirheumatics revenue the top 10 antirheumatics pharmaceutical companies in the world are:

1. AbbVie Inc. : USD 19.936 billion
2. Amgen Inc. : USD 5.014 billion
3. Pfizer Inc. : USD 4.572 billion
4. Roche Holding AG : USD 3.646 billion
5. Novartis AG : USD 3.391 billion
6. Johnson & Johnson : USD 3.164 billion
7. Bristol-Myers Squibb : USD 2.710 billion
8. Merck & Co., Inc. : USD 1.810 billion
9. UCB S.A. : USD 1.706 billion
10. Celgene Corportation : USD 1.608 billion

1 . 1. AbbVie Inc.

AbbVie Inc. is an American publicly traded biopharmaceutical company founded in 2013. It originated as a spin-off of Abbott Laboratories. AbbVie’s products are focused on treating conditions such as chronic autoimmune diseases in rheumatology, gastroenterology and dermatology; oncology, including blood cancers; virology, including hepatitis C virus (HCV) and human immunodeficiency virus (HIV); neurological disorders, such as Parkinson’s disease and multiple sclerosis; metabolic diseases, including thyroid disease and complications associated with cystic fibrosis; as well as other serious health conditions.

AbbVie is world's largest antirheumatics pharmaceutical company thanks to world’s best-selling drug Humira. Humira is used for treatment of multiple types of arthritis, spondylitis, psoriasis, colitis, crohn’s disease etc. In FY 2018 the company's overall revenue from it’s antirheumatics pharma portfolio was USD 19.936 billion.

2 . 2. Amgen Inc.

Amgen Inc. is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California.

Amgen is world's second largest antirheumatics pharmaceutical company thanks to Enbrel drug. Enbrel is co-produced by Pfizer and Amgen and used to treat used for treatment of rheumatoid arthritis (RA), psoriatic arthritis (PsA) etc. In FY 2018 the company's overall revenue from it’s antirheumatics pharma portfolio was USD 5.014 billion.

3 . 3. Pfizer Inc.

Pfizer Inc. is a research-based, global biopharmaceutical company headquartered in New York City, with its research headquarters in Groton.

Pfizer is world's third largest antirheumatics pharmaceutical company. In FY 2018 the company's overall revenue from it’s antirheumatics pharma portfolio (Enbrel, Celebrex, Xeljanz) was USD 4.572 billion.

4 . 4. Roche Holding AG

Founded in 1896, Roche Holding AG is one of the world’s largest biotech company, with products in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Roche is also the in the forefront in-vitro diagnostics and tissue-based cancer diagnostics.

Roche is world's fourth largest antirheumatics pharmaceutical company. In FY 2018 the company's overall revenue from it’s antirheumatics pharma portfolio (Rituxan, Actemra/RoActemra) was USD 3.646 billion. Rituxan is used to treat blood cancer, rheumatoid arthritis (RA) and certain types of vasculitis. Actemra/RoActemra on the other hand is used to manage rheumatoid arthritis (RA) and forms of juvenile idiopathic arthritis.

5 . 5. Novartis AG

Novartis AG is a Swiss multinational pharmaceutical company based in Basel, Switzerland. The company manufactures neuroscience, immunology, hepatology and dermatology, ophthalmology, oncology, diabetes, respiratory, cardio-metabolic, hypertension, biopharmaceuticals, anti-infectives, surgical and vision care pharma products.

Novartis is world's fifth largest antirheumatics pharmaceutical company. In FY 2018 the company's overall revenue from it’s antirheumatics pharma portfolio (Cosentyx, Ilaris) was USD 3.391 billion. Cosentyx is the first approved fully human monoclonal antibody which plays an important role in driving the body’s immune response in several disorders like ankylosing spondylitis (AS) and psoriatic arthritis (PsA). Ilaris is used for treatment of rheumatoid arthritis (RA), cryopyrin-associated periodic syndromes (CAPS), Tumor necrosis factor receptor associated periodic syndrome (TRAPS), Hyperimmunoglobulin D syndrome (HIDS)/Mevalonate kinase deficiency (MKD) and Familial Mediterranean fever (FMF).

6 . 6. Johnson & Johnson

Johnson & Johnson was incorporated in the State of New Jersey in 1887. It is organized into three business segments: Consumer, Pharmaceutical and Medical Devices.

Johnson & Johnson is world's sixth largest antirheumatics pharmaceutical company. In FY 2018 the company's overall revenue from it’s antirheumatics pharma portfolio (Simponi, Remicade, Stelara) was USD 3.164 billion. Simponi is used for treatment of rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis and ulcerative colitis. Remicade is co-developed by Johnson & Johnson along with Merck and used for treatment of rheumatoid arthritis (RA), psoriatic arthritis (PsA), crohn's disease, ankylosing spondylitis, ulcerative colitis and psoriasis. Stelara is used in treatment of psoriatic arthritis (PsA), plaque psoriasis and crohn’s disease.

7 . 7. Bristol-Myers Squibb Company

Bristol-Myers Squibb (BMS) is a global biopharmaceutical company founded in 1933 which focuses on discovering, developing and delivering innovative medicines for patients with serious diseases.

Bristol-Myers Squibb is world's seventh largest antirheumatics pharmaceutical company. In FY 2018 the company's overall revenue from it’s antirheumatics pharma portfolio (Orencia) was USD 2.710 billion. Orencia is used for treatment of rheumatoid arthritis (RA) and polyarticular juvenile idiopathic arthritis.

8 . 8. Merck & Co. Inc

Merck & Co., Inc. was founded in 1891 and delivers innovative health solutions through its prescription medicines, vaccines, biologic therapies and animal health products.

Merck & Co. is world's eighth largest antirheumatics pharmaceutical company. In FY 2018 the company's overall revenue from it’s antirheumatics pharma portfolio (Remicade, Simponi, Arcoxia) was USD 4.572 billion. Arcoxia is mainly used in treatment of rheumatoid arthritis (RA), psoriatic arthritis (PsA), osteoarthritis and ankylosing spondylitis.

9 . 9. UCB S.A.

UCB (Union Chimique Belge) S.A. is a global biopharmaceutical company which was founded in 1928, with a focus on neurology and immunology.

UCB is world's ninth largest antirheumatics pharmaceutical company. In FY 2018 the company's overall revenue from it’s antirheumatics pharma portfolio (Cimzia) was USD 1.706 billion. Cimzia is used to treat inflammatory TNF-mediated diseases such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis and crohn’s disease.

10 . 10. Celgene Corporation

Celgene Corporation is an integrated global biopharmaceutical company engaged primarily in the discovery, development and commercialization of innovative therapies for the treatment of cancer and inflammatory diseases through next-generation solutions in protein homeostasis, immuno-oncology, epigenetics, immunology and neuro-inflammation.

Celgene Corporation is world's tenth largest antirheumatics pharmaceutical company. In FY 2018 the company's overall revenue from it’s antirheumatics pharma portfolio (Otezla) was USD 1.608 billion. Otezla is used in treatment of psoriatic arthritis (PsA) and plaque psoriasis.

On 3rd January 2019, Bristol-Myers Squibb Company which was ranked 7th based on their FY 2018 antirheumatics revenue announced their plan to acquire Celgene Corporation which was ranked 10th in the world for antirheumatics revenue. The acquisition is expected to cost around USD 90 billion to Bristol-Myers Squibb Company. Post-acquisition Bristol-Myers Squibb Company is expected to give tough competition to Pfizer for 3rd spot in global antirheumatics revenue

Global antirheumatics pharmaceutical market is expected to be worth USD 56.88 billion by 2023.

 

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